The M80 Ring Road closes Greensborough-bound between Sydney and Edgars roads nightly from Sunday, March 6 to Thursday, March 10.
The closure will be between 10pm to 5am, as part of the M80 Upgrade.
There will be no access to the M80 from Sydney Road or the Hume Freeway during this time, the Department of Transport has advised.
Detour: Use Sydney Road, Mahoneys Road and Edgars Road to return to the freeway. Use Sydney Road and Cooper Street to reach the Hume Freeway.