The Hume Freeway will be reduced to one Melbourne-bound lane through Beveridge for three weeks from Sunday.
The lane closures will allow upgrades works to take place.
Motorists can detour by leaving the Hume Freeway at the Wandong or Wallan exit ramps and using Epping-Kilmore Road, Merriang Road and Donnybrook Road to return to the freeway, allowing up to 20 minutes extra for their journey.
Heavy vehicles are advised to remain on the Hume Freeway and allow extra time to travel through the work site.
Works are weather-dependent, so dates and times may change, according to the Department of Transport.
Real-time traffic conditions are available at traffic.vicroads.vic.gov.au or via the VicTraffic mobile app.
The latest public transport information and network status is available at ptv.vic.gov.au or in the PTV mobile app.
