Police are investigating a hit-run collision in Campbellfield on Monday night.
Police caught sight of a vehicle travelling at speeds of up to 199km/h in the vicinity of Barry Road about 11.10pm.
The white Audi took off at speed when it spotted the police car, before it collided with a silver Subaru at the corner of Barry and Sydney roads.
The driver of the Audi dumped the car and took off on foot.
The driver of the Subaru, a 21-year-old man, and only passenger, a 19-year-old man, were both taken to hospital with serious injuries.
Despite a thorough search of the area the driver of the Audi was not located.
Investigators are working to establish if the Audi was a stolen vehicle.
The investigation remains ongoing.
Professional Standards Command will have oversight of the investigation, as per standard procedure when there is a collision in close proximity to police.
Anyone with information can contact Crime Stoppers on 1800 333 000 or www.crimestoppersvic.com.au
